Figure 3.

Antiviral screening of drugs for repurposing at maximal nontoxic concentration against DENV under (a) pre-, (b) post-, and (c) co-treatment conditions. Vero CCL-81 cells were treated with a maximum non-toxic dose of drugs for 24 h in a pre-, co-, and post-infection manner and incubated for 120 h with DENV. Post incubation, plates were frozen and culture filtrates were used for different assays. Experiments were performed in triplicate in two independent trials. Results were plotted based on mean log10 of focus-forming unit/mL ± standard error. All the treatment groups were compared with a control group (VC) (infected cells without treatment). **** p < 0.0001, * p < 0.05.