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. 2022 Sep 23;14(10):2113. doi: 10.3390/v14102113

Table 1.

Viruses, separated by family, with inflammasome sensors activated and references associated with each one.

Family Virus Inflammasome Sensor(s) Activated Against Dichotomy? Reference(s)
Poxviridae Vaccinia AIM2 no [39]
Papillomaviridae HPV AIM2, IFI16 no [101,102]
Herpesviridae CMV AIM2 no [32]
HSV-1 NLRP3, AIM2, IFI16 yes [34,61,62,63,64]
KSHV IFI16 no [104]
Parvoviridae HBoV1 NLRP3 yes [33,65]
Hepadnaviridae HBV AIM2, NLRP3, NLRP1, NLRC4, IFI16 yes [35,53,66,67,68,69]
Adenoviridae Ad5 NLRP3, AIM2 yes [36,70,71,72]
Flaviviridae HCV NLRP3 no [22,94,105,106]
JEV NLRP3 no [111,112,113]
Dengue NLRP3 no [114,115,116,117,118]
CSFV NLRP3 no [119]
Zika NLRP1, NLRP3, AIM2 yes [37]
WNV RIG-I, NLRP1, NLRP3, AIM2 yes [73,74,75,76]
Pneumoviridae RSV NLRP3 no [120,121]
Phenuiviridae RVFV NLRP3 no [123]
Filoviridae Ebola NLRP3 no [129]
Coronaviridae SARS-CoV NLRP3 no [52,55,131,132,158]
SARS-CoV-2 NLRP3, AIM2, NLRP6 yes [10,88,155,156,157,158]
MHV NLRP3 no [133]
Rhabdoviridae Rabies NLRP3 no [18,134,135]
Hantaviridae Hantaan NLRP3 no [136]
Paramyxoviridae Measles NLRP3 no [137]
SeV NLRP3 no [138]
NDV NLRP3 no [47,139]
Picornaviridae EV71 NLRP3, AIM2 yes [23,77]
Togaviridae Mayaro NLRP3, AIM2 yes [20]
CHIKV AIM2, NLRP3 yes [76,78]
Orthomyxoviridae IAV NLRP3, RIG-I, IFI16, AIM2 yes [5,15,16,17,25,26,38,79,80,81,82,83,84,85,86,87]
Retroviridae HIV NLRP3, IFI16 yes [89,90,91,92,93]