Figure 5.
Representative photomicrographs showing the distribution of GPR41-, GRP43- or olfr78-immunoreactive cells (brown color) in the PVN of adult ND or HFD offspring, alone or with additional oral supplementation of FOS (4 g/kg/day, probiotic), L. gasseri (3 × 106 CFU/mL/day, probiotic) or FOS+L. gasseri (synbiotic) was initiated at the age of 6 weeks. 3V, third ventricle; PaMP, paraventricular nucleus, median pavicellularis; PaLM, paraventricular nucleus, lateral magnocellularis; PaV, paraventricular nucleus, ventrolaris. Scale bar: 500 μm.