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Tumor targeting of FRRG-MMAE nanoparticles. (a) NIRF images of 4T1 tumor-bearing mice treated with fluorescent dye Cy5.5-conjugated free MMAE or FRRG-MMAE. (b) Quantitative analysis for fluorescence intensities in the tumor regions of NIRF images. The statistical significance was indicated with asterisks *** p < 0.001 in the figures.
