Table 3.

Features with high correlation with the FNT SARA score and significant sensitivity to discriminate the control and SCA subjects.

		Mann–Whitney Test		Control/SCA Comparison
Phenotype	Feature	p-Value	Cohen’s d	Control	SCA	Diff (%)
Timing	Cycle time (s)	<0.01	1.33	1.02 ± 0.18	1.61 ± 0.47	−58
	Cycle per second	<0.01	2.65	0.99 ± 0.15	0.66 ± 0.12	34
	Pause at finger (s)	<0.01	0.86	0.01 ± 0.03	0.15 ± 0.18	−1187
	Pause at nose (s)	<0.01	0.67	0.003 ± 0.008	0.12 ± 0.20	−4866
Variability	STD of cycle time (s)	<0.01	0.50	0.05 ± 0.02	0.18 ± 0.27	−224
	STD of rise time (s)	<0.01	0.95	0.04 ± 0.03	0.09 ± 0.06	−139
	STD of ${\dot{\theta }}_y$ (deg/s)	<0.01	1.88	111.5 ± 8.9	77.0 ± 19.5	31
	STD of $\left|{\dot{\theta }}_y\right|$ (deg/s)	<0.01	1.25	63.4 ± 4.0	47.9 ± 13.4	24
	STD of pause at finger (s)	<0.01	0.95	0.015 ± 0.034	0.096 ± 0.092	−547
	STD of pause at nose (s)	<0.01	0.42	0.006 ± 0.019	0.074 ± 0.176	−1231
	STD of total pause (s)	<0.01	0.59	0.025 ± 0.053	0.155 ± 0.238	−527
Speed	max $\left({\dot{\theta }}_y\right)$	<0.01	0.98	197.8 ± 20.1	155.3 ± 46.3	22
	Range of ${\dot{\theta }}_y$	<0.01	1.15	397.8 ± 33.0	309.9 ± 82.1	22
	Average of $\left|{\dot{\theta }}_y\right|$	<0.01	2.19	91.9 ± 9.8	60.2 ± 15.2	35
	RMS of ${\dot{\theta }}_y$	<0.01	1.90	112.6 ± 9.2	77.4 ± 19.7	31
Rhythmicity	First RF of ${\dot{\theta }}_x$	<0.01	1.67	0.98 ± 0.19	0.67 ± 0.17	31
	First RF of ${\dot{\theta }}_y$	<0.01	1.87	1.01 ± 0.19	0.67 ± 0.18	34
	First MR of ${\dot{\theta }}_y$	<0.01	2.47	1.6 × 10−4 ± 4 × 10−3	71 × 10−4 ± 4 × 10−3	57
	First RF of $\ddot{x}$	<0.01	0.73	1.17 ± 0.52	0.78 ± 0.52	33
Steadiness	Jerk index of ${\dot{\theta }}_x$	<0.01	1.79	27.0 ± 6.7	18.1 ± 4.4	33
	Jerk index of MIAV	<0.01	1.35	12.6 ± 3.6	8.8 ± 2.6	30
	Second RF of ${\dot{\theta }}_x$	<0.01	1.79	2.92 ± 0.57	1.57 ± 0.77	46

Values are presented as mean ± standard deviation.