Table 2.

Description of patients with Lynch syndrome that developed colorectal cancer (n = 4).

Age at Cancer Diagnosis (Years)	Sex (M/F)	Lynch syndrome Associated Pathogenic Variant	Known Lynch syndrome Prior to Cancer Diagnosis?	Known Family History of Lynch syndrome at Diagnosis?	Cancer Type	Cancer Stage at Diagnosis	Current Status
17	M	MSH2 c.942+3A > T	No	Yes	Colon Adenocarcinoma	IIIC	No evidence of disease (NED) (∼1 year)
14	F	MLH1 c.2157dup	No	No	Rectal Adenocarcinoma	IV	Ongoing treatment
15	M	MSH2 c.942+3A > T	No	No (but likely)	Rectal Adenocarcinoma	IIIC	NED (∼4 years)
15	F	Likely PMS2	No	No	Colon Adenocarcinoma	IV	Ongoing treatment