Table 1.
Enzyme Inhibition data for Pyridine carboxamide and carbothioamide against Urease.
| Sr. No | Compound Name | Structure | IC50 ± SEM (µM) |
|---|---|---|---|
| 1. | RX-1 |
|
3.23 ± 0.015 |
| 2. | RX-2 |
|
6.41 ± 0.023 |
| 3. | RX-3 |
|
3.13 ± 0.034 |
| 4. | RX-4 |
|
4.21 ± 0.022 |
| 5. | RX-5 |
|
4.93 ± 0.012 |
| 6. | RX-6 |
|
1.07 ± 0.043 |
| 7. | RX-7 |
|
2.18 ± 0.058 |
| 8. | RX-8 |
|
3.41 ± 0.011 |
| 9. | RX-9 |
|
14.49 ± 0.067 |
| 10. | RX-10 |
|
5.52 ± 0.072 |
| 11. | RX-11 |
|
5.96 ± 0.005 |
| 12. | RX-12 |
|
4.07 ± 0.003 |
| 13. | * Thiourea | 18.93 ± 0.004 |
* standard inhibitor of urease.