Effects of S. polyanthum on the lipid profiles of streptozotocin-induced diabetic rats after 12-day twice-daily oral treatments. NC, normal control (normal saline, 10 mL/kg); DC, diabetic control (normal saline, 10 mL/kg); M, metformin (500 mg/kg); ME, methanol extract (1 g/kg); CF, chloroform fraction (500 mg/kg); SF-1, subfraction-1 (250 mg/kg); SQ, squalene (160 mg/kg); Chol, cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein. The values are expressed as mean ± SEM (n = 6); * p < 0.05 and *** p < 0.001 indicate significant differences compared to the DC as analyzed using Dunnett as post hoc test.