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. 2022 Oct 13;13:1004737. doi: 10.3389/fmicb.2022.1004737

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Copyright © 2022 Kepplinger, Wen, Tyler, Kim, Brown, Banks, Dashti, Mackenzie, Wills, Kawai, Waldron, Allenby, Wu, Hall and Errington.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative genomic analysis between Streptomyces drozdowiczii MDA8-470, Streptomyces coelicolor A3(2) and Actinosynnema mirum DSM 43827 in regards to the genetic locus of coelichelin and mirubactin. (Top) coelichelin biosynthetic gene cluster from Streptomyces coelicolor A3(2). (Middle) Genetic locus of the mirubactin and coelichelin gene cluster in Streptomyces drozdowiczii MDA8-470. (Bottom) mirubactin gene cluster from Actinosynnema mirum DSM 43827. Homology indicated by gray blocks based on BlastP analysis.