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. Author manuscript; available in PMC: 2022 Oct 27.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2021 Feb 1;110(4):1082–1089. doi: 10.1016/j.ijrobp.2021.01.043

Table 2:

Toxicity Details and Differences between Treatment Cohorts

IMRT (N=1282) PBT (N=568) Total (N=1850) P Value

Late GU Toxicity (any grade)
Frequency 267 (20.8%) 200 (35.2%) 467 (25.2%) <0.001
Urgency 256 (20.0%) 187 (32.9%) 443 (23.9%) <0.001
Obstruction 264 (20.6%) 103 (18.1%) 367 (19.8%) 0.221
Dysuria 252 (19.7%) 141 (24.8%) 393 (21.2%) 0.012
Stenosis 212 (16.5%) 87 (15.3%) 299 (16.2%) 0.511
Urinary Incontinence 258 (20.1%) 126 (22.2%) 384 (20.8%) 0.314
Cystitis 249 (19.4%) 97 (17.1%) 346 (18.7%) 0.233

Late GI Toxicity (any grade)
Diarrhea 253 (19.7%) 104 (18.3%) 357 (19.3%) 0.474
Proctitis 265 (20.7%) 132 (23.2%) 397 (21.5%) 0.214
Rectal Bleeding 295 (23.0%) 177 (31.2%) 472 (25.5%) <0.001
Bowel Incontinence 247 (19.3%) 96 (16.9%) 343 (18.5%) 0.227