Table 2:
Toxicity Details and Differences between Treatment Cohorts
IMRT (N=1282) | PBT (N=568) | Total (N=1850) | P Value | |
---|---|---|---|---|
| ||||
Late GU Toxicity (any grade) | ||||
Frequency | 267 (20.8%) | 200 (35.2%) | 467 (25.2%) | <0.001 |
Urgency | 256 (20.0%) | 187 (32.9%) | 443 (23.9%) | <0.001 |
Obstruction | 264 (20.6%) | 103 (18.1%) | 367 (19.8%) | 0.221 |
Dysuria | 252 (19.7%) | 141 (24.8%) | 393 (21.2%) | 0.012 |
Stenosis | 212 (16.5%) | 87 (15.3%) | 299 (16.2%) | 0.511 |
Urinary Incontinence | 258 (20.1%) | 126 (22.2%) | 384 (20.8%) | 0.314 |
Cystitis | 249 (19.4%) | 97 (17.1%) | 346 (18.7%) | 0.233 |
| ||||
Late GI Toxicity (any grade) | ||||
Diarrhea | 253 (19.7%) | 104 (18.3%) | 357 (19.3%) | 0.474 |
Proctitis | 265 (20.7%) | 132 (23.2%) | 397 (21.5%) | 0.214 |
Rectal Bleeding | 295 (23.0%) | 177 (31.2%) | 472 (25.5%) | <0.001 |
Bowel Incontinence | 247 (19.3%) | 96 (16.9%) | 343 (18.5%) | 0.227 |