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Immunogenicity and protectiveness of recombinant LSDV Atyrau-5BJN(IL18) in cattle. (A) Virus neutralizing antibody titers after immunization of animals. The circles indicate the values of the titer of virus-neutralizing antibodies for each animal. The lines show the mean and standard deviation. (B) The changes in body temperature of the cattle after vaccination or challenge. (C–E) Clinical signs of infection in control animals after challenge.
