Table 1.
Selected characteristics of gastric intestinal metaplasia (IM) patients and non-atrophic gastritis (NAG) controls
| Discovery set | Validation set | |||
|---|---|---|---|---|
| IM cases (n = 50) | NAG controls (n = 50) | IM cases (n = 100) | NAG controls (n = 100) | |
| Age in years, median (range) | 60 (35–73) | 55 (40–76) | 59 (39–79) | 54 (39–85) |
| Male sex, n (%) | 26 (52) | 14 (28) | 36 (36) | 23 (23) |
| H. pylori seropositivitya, n (%) | 27 (54) | 28 (56) | 61 (61) | 62 (62) |
| CagA serology, n (%) | 37 (74) | 19 (38) | 74 (74) | 41 (41) |
| H. pylori histologyb, n (%) | 19 (38) | 21 (42) | 47 (47) | 49 (49) |
| H. pylori urease test, n (%) | 21 (42) | 20 (40) | 49 (49) | 48 (48) |
| Overall H. pylori infectionc, n (%) | 43 (86) | 37 (74) | 90 (90) | 86 (86) |
| Past H. pylori infectiond, n (%) | 19 (38) | 15 (30) | 34 (34) | 32 (32) |
| Current H. pylori infectione, n (%) | 24 (48) | 22 (44) | 56 (56) | 54 (54) |
aELISA tested with H. pylori whole-cell lysate (wcELISA)
bModified Diff-Quick stain for H. pylori
cPositivity for either past or current H. pylori infection
dwcELISA( +) or CagA-ELISA( +) with histology(−) and urease(−) among individuals with overall H. pylori infection
eHistology( +) or urease( +), regardless of results on wcELISA and CagA-ELISA among individuals with overall H. pylori infection