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. 2022 Sep 29;14(10):2085. doi: 10.3390/pharmaceutics14102085

Table 1.

Flux of BD and Cal from commercially available topical formulations determined through in vitro Franz diffusion cells. When the values were not tabulated, the flux is calculated as the slope of the permeation profile curve. NA: not available.

Formulation Trade Name Skin Source Flux (ng/cm2 h−1) Reference
BD Cal
Ointment Daivonex® Pig NA * 6.7 ± 0.4 [22]
Diproderm® 50 ± 9 NA *
Ointment Generic product Human 2.81 ± 0.28 0.23 ± 0.04 [35]
Daivobet® 1.93 ± 0.29 0.13 ± 0.05
FoamOintment Enstillar® Pig -- * 0.005 Estimated from [27]
-- -- * 0.002
Oleogel/suspensionCream -- Human ~34 ~4 [31]
Wynzora® ~68 ~12

* below the limit of quantification.