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. 2022 Oct 5;14(10):2196. doi: 10.3390/v14102196

Table 4.

Sensitivities for the commercial assays in relation to sampling time following PCR positivity using the two-step ELISA as reference.

Assay Sensitivity (95% CI), Sampling 1–30 Days after Positive PCR Test, n = 36 Sensitivity (95% CI), Sampling 31–60 Days after Positive PCR Test, n = 76 Sensitivity (95% CI), Sampling 61–90 Days after Positive PCR Test, n = 15 Sensitivity (95% CI), Sampling 91–180 Days after Positive PCR Test, n = 25 Sensitivity (95% CI), Sampling 181–325 Days after Positive PCR Test, n = 43
Wantai RBD total antibody 97.1%
(85.5–99.5)
98.7%
(92.9–99.8)
93.3%
(70.2–98.8)
100%
(86.7–100)
97.7%
(87.9–99.6)
Liaison S1/S2 IgG 65.7%
(49.2–79.2)
93.4%
(85.5–97.2)
86.7%
(62.1–96.3)
88.0%
(70.0–95.8)
90.7%
(78.4–96.3)
Alinity i nucleocapsid IgG 74.3%
(57.9–85.8)
96.1%
(89.0–98.6)
66.7%
(41.7–84.8)
52.0%
(33.5–70.0)
37.2%
(24.4–52.1)

Abbreviations: RBD: receptor-binding domain, S1/S2: subunit 1/subunit 2, Ig: immunoglobulin, CI: confidence interval.