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. 2022 Sep 22;14(10):2016. doi: 10.3390/pharmaceutics14102016

Table 5.

Chemical structure representative of the cationic dendrimers developed in the last fifteen years that were active on pathogens’ BFs.

Dendrimers Structure Name Activity
graphic file with name pharmaceutics-14-02016-i001.jpg 2G3 IC50 = 0.025 µM
P. aeruginosa (PA) LecB
graphic file with name pharmaceutics-14-02016-i002.jpg (RW)4D Inactivate E. coli RP437
planktonic culture
and BFs
graphic file with name pharmaceutics-14-02016-i003.jpg FD2 LD50 LecB PA
0.14 µM
P. aeruginosa BF formation (IC50 = 10 mM)
D-FD2 LD50 LecB PA
0.66 µM
graphic file with name pharmaceutics-14-02016-i004.jpg PEGylated PAMAM Film on MAO Substrate BF by PA (strain PAO1) and S. aureus (SA).
graphic file with name pharmaceutics-14-02016-i005.jpg Nitric Oxide-Releasing amphiphilic PAMAM Inhibited PA BFs
graphic file with name pharmaceutics-14-02016-i006.jpg 14 Inhibited C. albicans BF
graphic file with name pharmaceutics-14-02016-i007.jpg G4 PAMAMs decorated with
C16-DABCO
Inhibited E. coli and
B. cereus BF
graphic file with name pharmaceutics-14-02016-i008.jpg PEGylated AgNPs covered with cationic carbosilane dendrons Inhibited E. coli and
S. aureus BF