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. 2022 Sep 22;14(10):2005. doi: 10.3390/pharmaceutics14102005

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of LEF suspension and LEF SPION EMLs on Bax and Bcl-2 ratio (A) and cleaved caspase-3 level (B) in joints of different experimental groups. Values are expressed as mean ± SD; n = 3. Statistical analyses were performed using one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test. # significant as compared to negative control group. & significant as compared to positive control group. @ significant as compared to LEF suspension. Significant difference was conducted at p < 0.0001.