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. 2022 Oct 14;14(10):2189. doi: 10.3390/pharmaceutics14102189

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Histological evaluations of bone formation at 4 weeks post-surgery (A) HE staining images of alveolar bone in control, hydrogel and hydrogel+exosome groups, respectively. Compared with the control and hydrogel groups, the hydrogel+exosome group had more new bone deposition. (B) Masson staining images of alveolar bone in control, hydrogel and hydrogel+exosome groups, respectively. Compared with the control and hydrogel groups, the hydrogel+exosome group had more new bone deposition. R: root; NB: new bone of periodontal regeneration.