Table 5.
Correlation between IL1β, IL4, IL-6, IL-18, and IL-35 with all parameters in the severe group.
| IL1β | IL4 | IL6 | IL18 | IL35 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R | p | R | p | R | p | R | p | R | p | |
| ALT (U/L) | 0.268 ** | 0.007 | 0.313 ** | 0.002 | 0.288 ** | 0.004 | 0.258 ** | 0.009 | 0.199 * | 0.047 |
| AST (U/L) | 0.203 * | 0.043 | 0.204 * | 0.042 | 0.286 ** | 0.004 | 0.232 * | 0.020 | 0.200 * | 0.046 |
| Albumin (g/dL) | −0.495 *** | 0.000 | −0.330 ** | 0.001 | −0.722 *** | 0.000 | −0.694 *** | 0.000 | −0.631 *** | 0.000 |
| CRP(mg/dL) | 0.548 *** | 0.000 | 0.400 *** | 0.000 | 0.838 *** | 0.000 | 0.737 *** | 0.000 | 0.685 *** | 0.000 |
| IL-1β (pg/mL) | 1 | 0.348 *** | 0.000 | 0.544 *** | 0.000 | 0.466 *** | 0.000 | 0.450 *** | 0.000 | |
| IL-4 (pg/mL) | 0.348 *** | 0.000 | 1 | 0.387 *** | 0.000 | 0.341 ** | 0.001 | 0.425 *** | 0.000 | |
| IL-6 (pg/mL) | 0.544 *** | 0.000 | 0.387 *** | 0.000 | 1 | 0.805 *** | 0.000 | 0.763 *** | 0.000 | |
| IL-18 (pg/mL) | 0.466 *** | 0.000 | 0.341 ** | 0.001 | 0.805 *** | 0.000 | 1 | 0.706 *** | 0.000 | |
| IL-35 (pg/mL) | 0.450 *** | 0.000 | 0.425 *** | 0.000 | 0.763 *** | 0.000 | 0.706 *** | 0.000 | 1 | |
| PGE2 (pg/mL) | 0.265 *** | 0.008 | 0.286 ** | 0.004 | 0.799 *** | 0.000 | 0.754 *** | 0.000 | 0.640 *** | 0.000 |
| TXA2 (pg/mL) | 0.530 *** | 0.000 | 0.432 *** | 0.000 | 0.775 *** | 0.000 | 0.670 *** | 0.000 | 0.632 *** | 0.000 |
| NF-κB p50 expression | 0.466 *** | 0.000 | 0.193 | 0.055 | 0.773 *** | 0.000 | 0.707 *** | 0.000 | 0.728 *** | 0.000 |
| NF-κB p65 expression | 0.390 *** | 0.000 | 0.293 ** | 0.003 | 0.838 *** | 0.000 | 0.785 *** | 0.000 | 0.669 *** | 0.000 |
| NRP-1 expression | 0.509 *** | 0.000 | 0.230 * | 0.021 | 0.811 *** | 0.000 | 0.731 *** | 0.000 | 0.708 *** | 0.000 |
Significance for correlation was calculated at three levels: * p < 0.05, ** p < 0.01, and *** p < 0.001.