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. 2022 Sep 29;10(10):1636. doi: 10.3390/vaccines10101636

Table 7.

AUC, sensitivity and specificity calculation for IL-6, TXA2, NF-κB p50, and NF-κB p65 in severe group.

AUC CI 95% p Cut-Off Value Sensitivity Specificity
IL-6 (pg/mL) 0.844 0.783–0.904 <0.001 51.0 pg/ml 100% 68%
TXA2 (pg/mL) 0.657 0.571–0.742 0.002 148.7 pg/ml 92% 53%
NF-κB p50
expression
0.765 0.690–0.839 <0.001 1.84 (relative to control) 74% 74%
NF-κB p65 expression 0.694 0.612–0.776 <0.001 3.25 (relative to control) 70% 60%