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. 2022 Oct 15;14(10):1981–2003. doi: 10.4251/wjgo.v14.i10.1981

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Relationships between cuproptosis-related long-chain non-coding RNA signature (CupRLSig) risk scores and somatic mutation and tumor mutation burden. A and B: Waterfall plots showing somatic mutations of the most significant 15 genes among high-risk (A) and low-risk (B) hepatocellular carcinoma (HCC) patients; C: Comparison of tumor mutation burden (TMB) between low- and high-risk subgroups; D: Kaplan-Meier curves for high- and low-TMB groups; E: Kaplan-Meier curves for subgroup analyses of patients stratified by TMB and risk score. The P value is representative of the results of the analysis of variance test among subgroups.