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. 2022 Oct 14;27(20):6900. doi: 10.3390/molecules27206900

Table 1.

Antibacterial activity of PTS and PTSO at different concentrations against pathogenic bacteria that infected S. aurata by the disk-diffusion method, expressed as the average diameter ± standard deviation of the inhibition zone (mm), along with EC50 values.

Compound Concentration (mg/mL) P. anguilliseptica T. maritimum P. damselae
subsp. Piscicida
P. damselae
subsp. damselae
PTS 2.5 12.5 ± 1.12 0.0 ± 0.00 0.0 ± 0.00 11.3 ± 0.83
5 17.5 ± 1.80 13.0 ± 1.41 11.0 ± 1.41 12.8 ± 1.09
10 19.5 ± 1.80 19.0 ± 2.24 26.3 ± 2.38 13.5 ± 1.12
25 23.5 ± 1.12 30.5 ± 1.80 35.0 ± 1.41 15.0 ± 0.71
50 29.8 ± 2.86 34.5 ± 1.12 43.8 ± 2.38 16.5 ± 1.80
EC50 1 (mg/mL) 12.7563 8.1651 8.9399 11.6285
PTSO 2.5 14.5 ± 1.12 28.5 ± 1.12 40.5 ± 1.66 18.8 ± 2.86
5 17.5 ± 1.80 39.0 ± 1.41 47.5 ± 1.80 24.5 ± 1.12
10 23.5 ± 1.80 45.5 ± 1.80 56.8 ± 2.86 30.5 ± 1.12
25 32.5 ± 1.12 59.0 ± 1.41 62.5 ± 2.96 39.0 ± 1.00
50 40.5 ± 1.12 66.5 ± 1.12 68.0 ± 2.24 43.5 ± 1.12
EC50 1 (mg/mL) 14.4796 10.5698 9.0014 10.4522

1 EC50: Half maximal effective concentration.