Table 6.
Animal ID | Group Description | Day of Death | Exposure Site | Lung | Heart | Adrenal Gland | Spleen | Liver | Axillary LN | Right Inguinal LN | Hilar LN |
---|---|---|---|---|---|---|---|---|---|---|---|
478 | SP-TK, Mock-exposed | S, Day 21 | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL |
495 | SP-TK, Mock-exposed | S, Day 21 | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL |
487 | SP-TK | S, Day 21 | 1.99 × 103 | BDL | 2.40 × 102 | BDL | 2.95 × 103 | 1.25 × 102 | 1.54 × 102 | 1.27 × 104 | 5.13 × 103 |
483 | SE | S, Day 2 | BDL | BDL | 6.73 × 102 | BDL | BDL | BDL | BDL | BDL | BDL |
491 | SE | S, Day 2 | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL | BDL |
481 | SE | S, Day 3 | 1.66 × 103 | BDL | 5.65 × 103 | 9.32 × 102 | 1.52 × 105 | 9.16 × 104 | 1.55 × 101 | BDL | BDL |
490 | SE | S, Day 3 | BDL | BDL | 3.83 × 102 | BDL | 3.62 × 103 | 1.93 × 103 | 1.94 × 105 | BDL | BDL |
484 | SE | S, Day 5 | 3.74 × 104 | BDL | 3.02 × 104 | 5.60 × 106 | 5.94 × 106 | 2.56 × 106 | 2.91 × 105 | 1.69 × 104 | 1.62 × 105 |
493 | SE | S, Day 5 | 1.28 × 105 | BDL | 1.25 × 106 | 3.75 × 106 | 1.15 × 108 | 8.04 × 107 | 1.00 × 103 | 2.16 × 106 | 3.20 × 106 |
477 | SE | S, Day 7 | 1.11 × 108 | BDL | 1.44 × 106 | 5.52 × 107 | 4.33 × 107 | 3.93 × 106 | 5.40 × 105 | 1.70 × 105 | 2.12 × 106 |
485 | SE | S, Day 7 | 1.19 × 106 | BDL | 1.28 × 105 | 1.05 × 106 | 2.30 × 106 | 9.76 × 105 | 3.97 × 106 | 1.26 × 106 | 3.03 × 106 |
476 | SE | S, Day 9 | 4.45 × 107 | 4.78 × 105 | 2.81 × 106 | 7.32 × 107 | 1.49 × 106 | 1.76 × 106 | 2.51 × 106 | 2.71 × 106 | 3.06 × 106 |
486 | SE | S, Day 9 | 5.61 × 107 | BDL | 3.01 × 106 | 7.93 × 106 | 1.98 × 106 | 8.86 × 105 | 1.26 × 106 | 1.72 × 106 | 2.98 × 106 |
479 | SP-TK | US, 7 | 1.06 × 108 | 4.13 × 105 | 3.25 × 106 | 1.04 × 107 | 7.14 × 107 | 4.09 × 106 | 2.57 × 106 | 3.45 × 106 | 3.93 × 106 |
482 | SP-TK | US, 8 | 3.62 × 106 | 1.17 × 105 | 2.75 × 106 | 3.54 × 106 | 5.21 × 106 | 2.03 × 106 | 2.51 × 106 | 5.48 × 105 | 4.22 × 106 |
492 | SP-TK | US, 8 | 5.12 × 106 | 2.04 × 105 | 1.98 × 106 | 1.19 × 108 | 7.72 × 107 | 1.12 × 106 | 1.51 × 106 | 1.11 × 106 | 9.29 × 105 |
474 | SP-TK | US, 9 | 2.75 × 105 | 3.26 × 105 | 2.12 × 106 | 3.49 × 107 | 4.36 × 106 | 1.14 × 106 | 1.36 × 106 | 5.60 × 105 | 2.50 × 106 |
488 | SP-TK | US, 9 | 7.51 × 107 | 4.54 × 104 | 5.59 × 105 | 1.85 × 106 | 3.92 × 105 | 7.96 × 105 | 7.72 × 105 | 1.12 × 106 | 9.74 × 105 |
480 | SP-TK | US, 11 | 5.95 × 107 | 3.34 × 106 | 4.24 × 106 | 6.19 × 106 | 1.73 × 106 | 1.35 × 106 | 8.61 × 106 | 2.40 × 106 | 2.19 × 106 |
494 | SP-TK | US, 13 | 3.57 × 106 | BDL | 8.50 × 104 | 2.35 × 106 | 3.17 × 105 | 3.68 × 105 | 8.58 × 106 | 3.75 × 105 | 1.02 × 105 |
SP-TK/CP-TK—Survival and Clinical Pathology Time Kinetics; SE—Serial Sample and Euthanasia; BDL—below detection limit (<10 GE/µg of RNA); S, scheduled; US, unscheduled.