Table 1.
mAb | Kinetic Affinity | Steady State | ||
---|---|---|---|---|
ka (M−1.s−1) | kd (s−1) | KD (M) | KD(M) | |
TT-117 | 6.33 × 103 | ND | ND | 2.58 × 10−7 |
TT-120 | 3.65 × 105 | 7.70 × 10−5 | 2.11 × 10−10 | 2.41 × 10−8 |
TT-140 | 8.65 × 104 | 3.92 × 10−5 | 4.54 × 10−10 | 1.10 × 10−7 |
TT-143 | 6.61 × 103 | ND | ND | 2.45 × 10−7 |
TT-243 | 7.68 × 103 | ND | ND | 6.08 × 10−7 |
ND = not determined. There was no dissociation in the period of the 36,000 s.