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. 2022 Oct 21;14(10):2314. doi: 10.3390/v14102314

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Substitution of SARS-CoV-2 lineages and its impact on local health. (A) Proportions of SARS-CoV-2 lineages found during the period of study. Viruses were classified based on genome sequencing and a specific RT-qPCR strategy capable of detecting specific mutations, as described in Section 2. EPLs, early pandemic lineages of SARS-CoV-2. (B) association between proportions of numbers of cases per month and numbers of deaths per month, as confirmed by linear regression analysis. (C) lack of association between proportions of viruses of the Gamma lineage found per month and proportions of cases per month (confirmed by linear regression analysis). (D) association between proportions of viruses of the Gamma lineage found per month and numbers of death per month (confirmed by linear regression analysis). Statistical significance was set as p ≤ 0.05.