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. 2022 Oct 21;10(10):1768. doi: 10.3390/vaccines10101768

Figure 1.

Figure 1

Homing receptor profiles of SPZ-specific B cells at different time points after vaccination and CHMI. Statistical analysis revealed that the frequency of CD69+ B cells expressing the skin-specific marker CCR10 (left panel), B cell compartment-specific CXCR5 (middle panel), and T cell compartment -specific CD197 (right panel) significantly change in the course of the immunization and after parasite challenge (infection) ((T0 = pre-immune, T1 = 2 weeks after the third immunization, T2 = 5–6 days after CHMI, T3 = 3–4 months after CHMI). Asterisk indicates statistical significance (* p < 0.05, ** p < 0.01, *** p < 0.001)).