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. 2022 Oct 21;10(10):1768. doi: 10.3390/vaccines10101768

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Homing receptor profiles induced by RAS vaccination. The relationship between expressed homing receptors on SPZ-specific lymphocytes was investigated by generating a correlation matrix including only homing receptors with significant altered expression after immunization or challenge. (A) Correlation matrix of these 12 parameters before immunization (T0); (B) after immunization (T1); (C) 5–6 days after CHMI (T2); (D) 3–4 months after CHMI (T3). Only significant correlations (p < 0.05) are shown. The color and size of the dots (scale next to graph) indicate the degree of correlation between the different parameters (small to large indicating low to high correlation).