Skip to main content
. 2022 Oct 21;10(10):1768. doi: 10.3390/vaccines10101768

Table 1.

Flow cytometric panel for the identification of homing receptors expressed by antigen-specific lymphocyte population.

Marker Receptor Type Ligand Function/Target Tissue
CD103 (ITGAE) Integrin E-cadherin Entry into epithelial tissues including liver, skin [31]
CD161 (KLRB1) C-type lectin LLT-1 Entry into inflamed tissue, liver (IL-17 driven) [32]
CD183 (CXCR3) Chemokine receptor CXCL9, CXCL10, CXCL11 Entry into inflamed tissue, liver [33]
CD185 (CXCR5) Chemokine receptor CXCL13 Entry into lymph nodes, direction towards B cell-compartment (follicles/germinal centers) [34]
CD186 (CXCR6) Chemokine receptor CXCL16 Entry into inflamed tissue, liver [33]
CD196 (CCR6) Chemokine receptor CCL20 Entry into inflamed tissue, Th17, skin [35]
CD197(CCR7) Chemokine receptor CCL19, CCL21 Entry into secondary lymphoid organs [33,36], direction towards T cell compartments [34]
CDw199 (CCR9) Chemokine receptor CCL25 Entry into intestinal tissues [37]
CCR10 Chemokine receptor CCL27, CCL28 Entry into Skin [35]