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. 2022 Oct 11;14(20):4225. doi: 10.3390/nu14204225

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hepatic mRNA levels in molecules involved in inflammation, fibrosis and lipid metabolism. Proinflammatory gene expression (A) Tnfa (p < 0.05) (B) Il6 (p < 0.05) (C) Il1b (p < 0.001) and (D) Nos2 are reduced after Mo supplementation compared to HF animals (p < 0.05 and p < 0.01). mRNA levels of the main fibro-genic molecules (E) Tgfb (p < 0.01) and (F) Srebf1 (p < 0.01) tent to be increase only in HF animals. Lipogenic genes evaluated: (G) Srebf1, (H) Fasn (p < 0.01), and (I) Dagt2 showed a reduction in Mo treated animals compared to HF group (p < 0.05). Data are expressed as mean ± SE. * p < 0.05; ** p < 0.01; *** p < 0.001.