Skip to main content
. 2022 Sep 27;14(10):2057. doi: 10.3390/pharmaceutics14102057

Table 1.

1H-NMR parameters and HR-ESI(+) mass spectrometry data for the mono-protonated species of taci·3HCl, taci·2H2O, cationic complex 1, its hydrolyzed products: h1, h2, h3 and cationic complex 2.

Compound pH 1H NMR,
δ [ppm], J [Hz]
HR-ESI(+)-MS Data, m/z
/Main Peak for [comp.]+/
δ, H-(C-NH2)/
  3JHH /3JPtH
δ, H-(C-OH)/
  3JHH
Composition Observed Mass, Da Calculated Mass, Da Error [ppm]
taci·3HCl 3.0 3.69/3.28/- 4.43/3.24 [C6H15N3O3-H]+ 178.1197 178.1192 2.81
taci·2H2O 9.5 2.76/3.00/- 3.82/2.98 [C6H15N3O3-H]+ 178.1196 178.1192 2.25
fac-[Pt(taci)I3]+, 1 5.5 3.28/4.42 47.0 4.43/4.30 [C6H15N3O3I3Pt]+ 752.7895 752.7895 0.66
fac,cis-[Pt(taci)I2OH]+, h1 7.4 3.43/4.36/48.0 4.35/4.30 [C6H16N3O4I2Pt]+ 642.8875 642.8873 0.31
2.91/4.30/33.1 4.50/n.a.
fac,cis-[Pt(taci)I(OH)2]+, h2 7.4 3.48/4.30/49.0 4.41/4.34 [C6H17N3O5IPt]+ 532.9865 532.9855 1.88
3.10/4.30/38.3 4.27/4.34
fac-[Pt(taci)(OH)3]+, h3 7.4 3.23/4.25/41.7 4.35/4.22 [C6H18N3O6Pt]+ 423.0836 423.0838 0.47
bis-[Pt{(taci)2-3H}]+, 2 9.5 3.04/4.30/42.3 4.33/4.30 [C12H27N6O6Pt]+ 546.1643 546.1643 0.37