Table 3.
Multivariable logistic regression models. Without adjusting for species, age, and sex (Model 0) and with adjustments (Model 1) for risk factors for malignant tumors in the Vet-OncoNet database. Topography of tumors (topography group), breed, and geographical location (district) were considered as random effects.
| Variable | Category | Model 0 | Model 1 | |||
|---|---|---|---|---|---|---|
| OR | 95%CI | OR | 95%CI | p-Value | ||
| Dogs and cats | ||||||
| Species | ||||||
| Canine | - | - | Ref | |||
| Feline | - | - | 3.96 | (3.57, 4.39) | <0.001 | |
| Age (3y) | 1.18 | (1.14, 1.23) | <0.001 | |||
| Sex | ||||||
| Male | - | - | Ref | |||
| Female | - | - | 1.19 | (1.09, 1.30) | <0.001 | |
| Random Effect | MOR | Variance | MOR | Variance | ||
| Topography | 4.26 | 2.314 | 4.10 | 2.188 | ||
| District | 1.09 | 0.009 | 1.14 | 0.019 | ||
| Dogs | ||||||
| Age (3y) | - | - | 1.24 | (1.19, 1.29) | <0.001 | |
| Sex | ||||||
| Male | - | - | Ref | |||
| Female | - | - | 1.19 | (1.08, 1.31) | <0.001 | |
| Random Effect | MOR | Variance | MOR | Variance | ||
| Topography | 4.33 | 2.364 | 4.25 | 2.301 | ||
| Breed | 1.53 | 0.198 | 1.56 | 0.221 | ||
| District | 1.09 | 0.009 | 1.11 | 0.013 | ||
| Cats | ||||||
| Age (3y) | - | - | 1.23 | 1.13, 1.34 | <0.001 | |
| Sex | - | - | ||||
| Male | - | - | Ref | |||
| Female | - | - | 0.98 | 0.77, 1.23 | 0.872 | |
| Random Effect | MOR | Variance | MOR | Variance | ||
| Topography | 6.44 | 3.811 | 6.05 | 3.563 | ||
| Breed | 1.38 | 0.117 | 1.43 | 0.140 | ||
| District | 1.19 | 0.034 | 1.19 | 0.035 | ||
Total number of cases included in this analysis: malignant tumors: 8083, benign tumors: 7208. Only breeds with more than 30 records were included.