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(A) FTIR spectra and (B) ZP and HD values of Bi-nano upon conjugation with iRGD peptides. (C) MTT results of the effects of targeting of the nanostructure by iRGD peptides in contact with the U87 cancer cell line and HEK 293T normal cell line (inset). (D) Effects of iRGD conjugation on the intracellular ROS generated by normal and cancer cells after 15 and 60 min of incubation (binanozyme concentration in the MTT and ROS experiments: 3.5 μg/mL//15 μg/mL, AuNP//Co-MION).
