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Synthesis of DOX-loaded PEG-CCM@APTES-COF-1 with cellular uptake at weak acidic tumor tissue/cells (a–d). (e) Synthesis of PEG-CCM amphiphilic block copolymers containing hydrophobic blocks based on the unplugging of the PEG-CCM polymer from the APTES-COF-1 pores [108]. Reprinted with permission from ref. [108]. Copyright 2018 Springer Nature.
