Table 2.
The PCA-X mode, OPLS-DA mode, and 999-permutation were used for multivariate exploration of clusters and trends among two groups of male and female in seven tissues.
Tissues | PCA-X | OPLS-DA | 999-Permutation | Wilcoxon Test Differential/All | |||
---|---|---|---|---|---|---|---|
R2X | Q2 | R2Y | Q2 | R2 | Q2 | ||
Heart | 0.677 | 0.347 | 0.735 | 0.032 | 0.484 | −0.321 | 2/55 |
Liver | 0.917 | 0.767 | 0.871 | 0.717 | 0.845 | −0.707 | 16/53 |
Spleen | 0.594 | 0.259 | 0.999 | 0.897 | 0.928 | −1.780 | 4/52 |
Lung | 0.503 | 0.101 | 0.699 | −0.072 | 0.703 | −0.292 | 1/49 |
Kidney | 0.720 | 0.279 | 0.946 | 0.579 | 0.844 | −0.760 | 21/56 |
Brain | 0.709 | −0.210 | 0.529 | −0.371 | 0.460 | −0.360 | 0/42 |
Skeletal muscle | 0.755 | 0.386 | 0.680 | 0.045 | 0.384 | −0.371 | 8/57 |
Differential/all: differential is CL which has a significant difference, by Wilcoxon–Mann–Whitney test, in every tissue. All is all CL quantified in every tissue.