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The expression of ERK1/2 and pERK1/2 in pneumocytes, PAMs (top row) and bronchial epithelial cells (bottom row) of dogs in the control (a,d,g,j), degenerative mitral valve disease (DMVD) (b,e,h,k) and degenerative mitral valve disease with pulmonary hypertension (DMVD with PH) groups (c,f,i,l) presented as brown color (Labeled streptavidin-biotin, Immunohistochemistry, Mayer’s Hematoxylin counterstained, 400× magnification).
