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Cytotoxic activity (IC50, 72 h) for IBC and its analogs against five cancer cell lines.
| Compounds | MDA-MB-231 | MCF-7 | SMMC-7721 | CNE-2Z | H1975 |
|---|---|---|---|---|---|
| IBC | 8.53 | >25.0 | 12.95 | >25.0 | 14.54 |
| isoliquiritigenin | >25.0 | 16.26 | >25.0 | 23.40 | >25.0 |
| isobavachin | >25.0 | >25.0 | >25.0 | >25.0 | >25.0 |
| bavachin | 16.95 | >25.0 | >25.0 | 23.51 | >25.0 |
| bavachinin | 22.08 | >25.0 | >25.0 | >25.0 | >25.0 |
| shikonin a | 1.27 | 1.35 | 0.59 | 3.87 | 3.18 |
a positive control.
