2APB	2-aminoethoxy diphenylborinate
ADP	Adenosine diphosphate
ASC	Apoptosis-associated speck-like protein containing a caspase-recruitment domain
ASICs	Acid-sensing ion channels
ASK1	Apoptosis signal-regulating kinase 1
ATP	Adenosine triphosphate
BBB	Blood brain barrier
BHB	Beta-hydroxybutyrate
BTK	Bruton’s tyrosine kinase
CARD	Caspase activation and recruitment domain
CASr	Calcium-sensing receptor
CIAS-1	Cold-induced autoinflammatory syndrome 1
CNS	Central nervous system
CPT1A	Carnitine palmitoyltransferase 1A
DAMPs	Damage-associated molecular patterns
ER	Endoplasmic reticulum
ERK	Extracellular signal-regulated kinases
FADD	Fas-associated protein with death domain
Fendrr	LncRNA FOXF1 adjacent non-coding developmental Regulatory RNA
GPRC6A	G protein-coupled receptor family C group 6 member A
GSDMD	Gasdermin D
HERC2	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2
IFN	Interferon
IFNAR	Interferon-α/β receptor
IL-18	Interleukin-18
IL-1β	Interleukin-1 β
IP3	Inositol 1,4,5-triphosphate
IP3R	IP3 receptor
JAK	Janus kinase
JNK	c-Jun N-terminal kinases
LPC	Lysophosphatidylcholine
LPS	Lipopolysaccharide
LRR	Leucine-rich repeat
MAM	Mitochondria-associated membrane
MAPK	Mitogen-activated protein kinase
MAVS	Mitochondrial antiviral-signaling protein
MCC950	1-(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea
MCP-1/CCL2	Monocyte Chemoattractant Protein-1
MMPs	Matrix metalloproteinases
MSU	Monosodium urate
mtROS	Mitochondrial ROS
Myd88	Myeloid differentiation primary response 88
NADPH	Nicotinamide adenine dinucleotide phosphate
NF-κB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NLR	NOD-like receptor
NLRC4	NLR Family CARD-Domain-Containing 4
NLRP1	NLR family pyrin-domain-containing 1
NLRP2	NLR family pyrin-domain containing 2
NLRP3	NLR family pyrin-domain-containing 3
NMDA	N methyl D aspartate
NO	Nitric oxide
NOD	Nucleotide-binding oligomerization domain
NOX2	NADPH oxidase 2
NOX4	NADPH oxidase 4
NRF2	Nuclear factor erythroid-2 related factor 2
NVU	Neurovascular unit
OGD	Oxygen-glucose deprivation
P2X7R	P2X purinoceptor 7
PAMPs	Pathogen Associated Molecular Patterns
PIP2	Phosphatidylinositol 4,5-bisphosphate
PLA2	Phospholipase A2
PRRs	Pattern recognition receptors
PYD	Pyrin domain
PYHIN	Pyrin and HIN domain
RAGE	Receptor for advanced glycation end-products
ROS	Reactive oxygen species
RIPK1	Receptor-interacting serine/threonine-protein kinase 1
STAT1	Signal transducer and activator of transcription 1
STAT3	Signal transducer and activator of transcription 3
TAK1	Transforming growth factor beta-activated kinase 1
tMCAO	Transient middle cerebral artery occlusion
TLRs	Toll-like receptors
TRAF3	TNF-receptor-associated factor 3
TRAF6	TNF-receptor-associated factor 6
TRPM	Transient receptor potential ion melastatin
TRPV	Transient receptor potential ion vanilloid
TXNIP	Thioredoxin-interacting protein
VDAC	Voltage-dependent anion channel