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. 2022 Sep 21;15(10):1168. doi: 10.3390/ph15101168

Table 1.

Direct and indirect inhibitors of the NLRP3 inflammasome in ischemic stroke.

Categories Drugs or Molecules References
Acting on gene expression products MCC950, Bay 11-7082, NRF2, sinomenine, curcumin, minocycline [92]
Acting on the process of gene expression IVIG, IFN-β, ketone metabolite hydroxybutyrate, probenecid, nafamostat mesilate [92]
Acting on gene expression processes and gene expression products miR-223, miR-155, resveratrol [92]

IFN-β, Interferon-β, IVIG, intravenous immune globulin, NRF2, Nuclear factor erythroid 2-related factor 2, mir-155, MicroRNA-155, mir-223, MicroRNA-223.