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. 2022 Oct 20;15(10):1295. doi: 10.3390/ph15101295

Figure 1.

Figure 1

The siRNA mechanism of action. The antisense strand of the siRNA is up-taken by a catalytic protein complex (RNA-induced silencing complex, RISC). The antisense strand drives RISC to a target mRNA, which results in specific, RISC-mediated mRNA degradation.