Table 3:
Hazard Ratio (95% Confidence Interval) of Abdominal Aortic Aneurysm per Standard Deviation Increment of White Blood Cell Differential Count Among Never Smokers, in the Atherosclerosis Risk in Communities Study, 1987–1989 to 2011.
Standard Deviation, SD, cells/μl | HR* per SD increase (95% CI) |
|||
---|---|---|---|---|
Model 1 | Model 2 | Model 3 | ||
| ||||
Neutrophils | 1252 | 1.33 (1.02–1.74) | 1.27 0.96–1.58) | 1.29 (1.00–1.80) |
Monocytes | 157 | 1.36 (1.07–1.74) | 1.36 (1.03–1.81) | 1.35 (1.02–1.79) |
Lymphocytes | 600 | 0.83 (0.59–1.17) | 0.76 (0.52–1.09) | 0.74 (0.51–1.09) |
Eosinophils | 126 | 1.20 (1.00–1.54) | 1.31 (1.02–1.69) | 1.31 (1.01–1.69) |
Basophils | 39 | 0.81 (0.57–1.15) | 0.76 (0.53–1.09) | 0.73 (0.51–1.05) |
HR (hazard ratio) per SD (standard deviation) increase in exposure.
Out of 4533 participants who were never smokers, 44 participants developed AAA over the follow-up. Incidence rate among never smokers at baseline was 46.6 per 100,000 person years.
Model 1: adjusted for age, sex and race-center
Model 2: adjusted for Model 1 covariates plus other differentials
Model 3: adjusted for Model 2 covariates plus height, total cholesterol, HDL cholesterol, triglycerides, use of cholesterol lowering medication, hypertension, diabetes, peripheral artery disease, and prevalent coronary heart disease at Visit 1