Table 1. iPSC CRISPR-Cas9 engineered lines.
Donor line | CRISPR-Cas9 engineered PRNP 200 genotypes | |||
---|---|---|---|---|
Name | PRNP 129 genotype | PRNP 200 genotype | ||
E200K donor | M/M | E/K | E/E | K/K |
No Known Disease (NKD) donor | M/M | E/E | E/K | K/K |
Donor line | CRISPR-Cas9 engineered PRNP 200 genotypes | |||
---|---|---|---|---|
Name | PRNP 129 genotype | PRNP 200 genotype | ||
E200K donor | M/M | E/K | E/E | K/K |
No Known Disease (NKD) donor | M/M | E/E | E/K | K/K |