Fig 2. Kaplan-Meier analyses of all-cause mortality and the new emergence of HCC post-SVR stratified by 4COL7S-defined fibrosis progression_SVR and regression_SVR.

A comparison of 4COL7S-defined fibrosis progression_SVR and regression_SVR (refer to the main text for definition), all-cause mortality (in panel A), and cumulative frequency of newly emerged HCC (in panel B) is evaluated from SVR12 in 326 IFN-free DAA-treated patients achieving SVR (whole cohort). All-cause mortality (in panel C) and accumulative frequency of newly emerged HCC (in panel D) are evaluated based on the SVR12 of patients with baseline serum levels of 4COL7S≥ 6.1 ng/mL (n = 163). **P < 0.01; ****P <0.0001.