Skip to main content
. 2022 Oct 27;17(10):e0276925. doi: 10.1371/journal.pone.0276925

Fig 3. Associations between the serum dynamics of 4COL7S and MMP and TIMP-1 ratios from pre-treatment to end of treatment (exploratory analysis 1).

Fig 3

Of 23 IFN-free DAA-treated patients achieving SVR, serum MMP2/TIMP-1 ratios at pre and EOT (in panel A) and serum MMP9/TIMP-1 ratios at pre and EOT (in panel B) are shown comparing 4COL7S-defined fibrosis progressionEOT (yellow squares) and regressionEOT (clear circles). (C) The relationships of pre-treatment MMP2/TIMP-1 and MMP9/TIMP-1 at EOT presented with 4COL7S-defined fibrosis progression (yellow squares) and regression (clear circles) at EOT are shown. Data are presented as medians with interquartile ranges. *P < 0.05.