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. 2022 Oct 27;17(10):e0276461. doi: 10.1371/journal.pone.0276461

Table 1. Demographic characteristics of the study population.

Pre-Pandemic* Pandemic* Standardized Mean Difference**
n 7,048,075 3,387,469
Female 48.9% 48.9% 0.00
Age
    < 1 2.2% 2.1% -0.04
    1–5 25.9% 25.6% -0.01
    6–12 40.6% 40.4% -0.01
    13–17 31.3% 31.9% 0.02
Race/Ethnicity (excluding unknown)
    non-Hispanic White 69.7% 70.5% 0.04
    non-Hispanic Black 8.1% 7.9% -0.04
    Hispanic 15% 14.4% -0.05
    Asian 7.2% 7.2% 0.01
Unknown Race/Ethnicity 16.5% 42.3% -
Census Region
    New England 2.5% 2.8% 0.09
    Middle Atlantic 6.4% 6.4% 0.00
    East North Central 15.2% 15.6% 0.03
    West North Central 11.4% 13% 0.15
    South Atlantic 20% 20.4% 0.03
    East South Central 3.7% 3.8% 0.03
    West South Central 17.5% 15.7% -0.13
    Mountain 10.9% 10.8% -0.01
    Pacific 12.4% 11.6% -0.07
Income quartile (of patient zip code)
    Lowest (< $55,019) 21.8% 21% -0.04
    Second ($55,020 - $72,759) 25.1% 25.1% 0.00
    Third ($72,759 - $96,969) 26.7% 27% 0.02
    Highest (> $96,969) 26.5% 26.8% 0.02

*Pre-pandemic period corresponds to January 2016 until mid-March 2020. Pandemic period corresponds to mid-March 2020 through March 2021.

**Standardized mean differences can be interpreted using Cohen’s guideline: d = 0.2 corresponds to a small difference; d = 0.5, to a medium difference; and d = 0.8 to a large difference.