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. 2022 Oct 27;17(10):e0276927. doi: 10.1371/journal.pone.0276927

Table 5. BWBP parameters at all three examination time points in cats with FLAD.

BWBP parameter Unit Day 0 Day 14 Day 60 p p day 0–14 p day 0–60 p day 14–60
RR breaths/min 61.8 (43.0–91.9) 59.6 (36.6–83.8) 61.2 (35.6–95.7) 0.59 n.a.
Ti s 0.4 (0.3–0.6) 0.4 (0.3–0.7) 0.4 (0.3–0.7) 0.59 n.a.
Te s 0.6 (0.4–0.9) 0.6 (0.5–1.1) 0.6 (0.4–1.0) 0.47 n.a.
TV ml 23.0 (14.2–33.5) 21.5 (15.6–27.6) 20.9 (16.2–29.4) 0.96 n.a.
TV/BW ml/kg 4.8 (3.0–7.3) 4.7 (3.2–8.0) 4.8 (3.4–6.8) 0.59 n.a.
MV ml/min 1138.5 (989.9–1687.1) 1192.4 (885.8–1487.9) 1238.8 (956.3–1658.5) 0.29 n.a.
MV/BW ml/min/kg 261.9 (242.2–345.2) 246.0 (201.2–301.2) 253.6 (212.6–311.1) 0.43 n.a.
PIF ml/s 75.8 (66.3–108.2) 78.5 (57.0–92.6) 73.2 (67.5–93.2) 0.29 n.a.
PIF/BW ml/s/kg 17.9 (13.9–22.7) 16.2 (13.5–20.8) 16.4 (13.7–19.4) 0.76 n.a.
PEF ml/s 49.0 (45.2–74.6) 48.6 (36.3–53.5) 46.4 (39.0–58.6) 0.29 n.a.
PEF/BW ml/s/kg 11.4 (9.2–16.2) 9.9 (9.0–11.2) 10.2 (8.0–14.3) 0.59 n.a.
EF50 ml/s 41.6 (30.4–63.6) 38.7 (27.7–46.5) 40.1 (27.8–54.6) 0.70 n.a.
RT ms 0.3 (0.2–0.5) 0.4 (0.3–0.5) 0.3 (0.2–0.5) 0.14 n.a.
EIP ms 12.0 (10.4–14.9) 13.4 (11.7–18.1) 12.6 (10.7–15.8) 0.10 n.a.
EEP ms 3.9 (1.8–23.0) 6.3 (1.3–15.5) 3.0 (1.5–12.9) 0.62 n.a.
PAU unitless 0.9 (0.7–1.0) 0.8 (0.7–0.9) 0.8 (0.8–0.9) 0.59 n.a.
Penh unitless 0.7 (0.5–0.8) 0.5 (0.4–0.6) 0.5 (0.4–0.8) 0.02 0.009 0.65 0.03
PEF/EF50 unitless 1.2 (1.1–1.4) 1.2 (1.1–1.3) 1.2 (1.1–1.3) 0.47 n.a.

Data are presented as median with IQR. Bold values indicate p<0.05. The last three columns show the corrected values between the individual time periods. Bold values between individual time periods indicate p<0.017. Not applicable (n.a.). Respiratory rate (RR; breaths/minute), inspiratory time (Ti; s), expiratory time (Te; s), tidal volume (TV; mL), tidal volume per body weight (TV/BW [mL/kg]), minute volume (MV; mL/min), minute volume per body weight (MV/BW; [mL/min/kg]), peak inspiratory pseudo-flow (PIF; mL/s), peak inspiratory pseudo-flow per body weight (PIF/BW; [mL/s/kg]), peak expiratory pseudo-flow (PEF; mL/s), peak expiratory pseudo-flow per body weight (PEF/BW; [mL/s/kg]), expiratory flow at end tidal volume plus 50% tidal volume (EF50; mL/s), relaxation time (RT; ms; time point when 65% of tidal volume is expired), end inspiratory pause (EIP; ms), end expiratory pause (EEP; ms), pause (PAU; unitless; (Te-RT)/RT), enhanced pause (Penh; unitless; (PEF/PIF)x(Te-RT)/RT) and quotient of peak expiratory pseudo-flow divided by expiratory flow at end expiratory volume plus 50% tidal volume (PEF/EF50; unitless).