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. 2022 Oct 27;17(10):e0274195. doi: 10.1371/journal.pone.0274195

Table 1. Baseline characteristics of participants according to the quartile groups of fasting blood glucose levels (N = 19,050).

Characteristic Overall Fasting blood glucose level
Quartile 1(<88, n = 4,726) Quartile 2(≥88, <97, n = 4,961) Quartile 3(≥97, <109, n = 4,709) Quartile 4(≥109, n = 4,654) P-for trend*
Person-year (total) 82,276.8 20,541.9 21,528.3 20,417.2 19,789.4
Person-year (average) 4.32 ± (0.69) 4.35 ± (0.65) 4.34 ± (0.65) 4.33 ± (0.65) 4.25 ± (0.79) <0.001
Age (years) 64.5 ± (10.1) 64.0 ± (10.5) 64.1 ± (10.3) 64.5 ± (10.1) 65.5 ± (9.6) <0.001
Gender <0.001
 Male (%) 12,312 (64.6) 2,823 (59.7) 3,024 (60.9) 3,153 (67.0) 3,312 (71.2)
 Female (%) 6,738 (35.4) 1,903 (40.3) 1,937 (39.1) 1,556 (33.0) 1,342 (28.8)
BMI (kg/m2) 23.9 ± (3.0) 23.5 ± (2.9) 23.8 ± (2.9) 24.1 ± (3.0) 24.5 ± (3.2) <0.001
Systolic BP (mmHg) 127.5 ± (15.8) 125.2 ± (15.6) 126.5 ± (15.5) 127.9 ± (15.7) 130.4 ± (15.9) <0.001
Diastolic BP (mmHg) 78.0 ± (9.9) 76.7 ± (9.8) 77.6 ± (9.8) 78.5 ± (9.9) 79.3 ± (10.0) <0.001
Total cholesterol (mg/dL) 195.3 ± (38.0) 192.4 ± (36.9) 195.7 ± (36.7) 197.9 ± (38.0) 195.2 ± (40.2) <0.001
Triglyceride (mg/dL) 120 (85–172) 109.5 (79–153) 115 (83–163) 123 (83–176) 137 (97–201) <0.001
HDL-cholesterol (mg/dL) 54.0 ± (33.5) 54.7 ± (29.3) 56.0 ± (38.1) 55.5 ± (35.4) 52.9 ± (30.3) 0.012
LDL-cholesterol (mg/dL) 113.9 ± (38.3) 113.7 ± (38.0) 115.4 ± (37.7) 115.9 ± (38.1) 110.7 ± (39.2) 0.001
SCr (mg/dL) 1.16 ± (1.39) 1.10 ± (1.27) 1.15 ± (1.42) 1.20 ± (1.49) 1.20 ± (1.40) <0.001
eGFR (mL/min per 1.73m2) 76.3 ± (19.9) 78.0 ± (19.7) 76.9 ± (19.5) 75.8 ± (20.2) 74.5 ± (20.1) <0.001
AST (U/L) 24 (20–30) 24 (20–29) 24 (20–29) 24 (20–30) 25 (20–33) <0.001
ALT (U/L) 21 (16–29) 19 (15–26) 20 (15–27) 21 (16–29) 24 (17–34) <0.001
GGT (U/L) 26 (18–45) 23 (16–37) 24 (17–39) 27 (18–46) 33 (21–60) <0.001
Smoking amount (pack-year) 11.6 ± (18.6) 10.6 ± (17.8) 10.2± (17.3) 12.0 ± (18.9) 13.8 ± (20.2) <0.001
Alcohol intake (%) 18.7 14.3 16.2 20.3 24.2 <0.001
Physical activity (%) 13.0 11.7 13.2 13.3 14.0 <0.001
Presence of DM (%) 3914 (20.6) 513 (10.8) 564 (11.4) 751 (15.9) 2086 (44.8) <0.001
Development of pancreatic cancer (%) 381 (2.00) 63 (1.33) 92 (1.85) 94 (2.00) 132 (2.84) <0.001

Data are means (standard deviation), medians (interquartile range), or percentages.

*P-value by ANOVA-test for continuous variables and Chi square test for categorical variables.