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. 2022 Oct 27;17(10):e0274195. doi: 10.1371/journal.pone.0274195

Table 2. Hazard ratios (HRs) and 95% confidence intervals (CI) for the incidence of pancreatic cancer according to the quartile groups of fasting blood glucose levels.

Person-years Incidence cases Incidence density (per 10,000 person-years) HR (95% CI) *
Unadjusted Multivariate adjusted model
Fasting blood glucose levels
 Quartile 1 20,541.9 63 30.7 1.00 (reference) 1.00 (reference)
 Quartile 2 21,528.3 92 42.7 1.39 (1.01–1.92) 1.47 (1.05–2.04)
 Quartile 3 20,417.2 94 46.0 1.50 (1.09–2.07) 1.61 (1.16–2.23)
 Quartile 4 19,789.4 132 66.7 2.18 (1.62–2.95) 2.31 (1.68–3.17)
P for trend <0.001 <0.001
Age 0.998 (0.987–1.010)
Gender (female vs male) 0.969 (0.752–1.249)
BMI 0.982 (0.948–1.018)
Systolic BP 0.999 (0.992–1.006)
Total cholesterol 0.999 (0.997–1.002)
GGT 1.000 (0.999–1.001)
eGFR 1.000 (0.995–1.006)
Smoking amount (pack-year) 1.000 (0.993–1.006)
Alcohol intake 0.964 (0.722–1.286)
Physical activity 0.946 (0.694–1.290)

Multivariate adjusted model was adjusted for age, gender, BMI, systolic BP, total cholesterol, GGT, eGFR, smoking amount (pack-year), alcohol intake and physical activity.