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. 2022 Oct 27;7:127. doi: 10.1038/s41541-022-00550-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The model-predicted RSV hospitalizations per 100,000 people by age is plotted for: A maternal immunization, B extended half-life monoclonal antibodies, and C live-attenuated vaccines. The green lines show the mean RSV hospitalization incidence by age (on the x-axis) assuming no vaccination. The orange lines show the model-predicted RSV hospitalization incidence by age in Year 7 following introduction of the intervention accounting only for the direct effects of RSV prevention strategies (i.e. assuming no reduction in RSV transmission). The purple lines show the model-predicted RSV hospitalization incidence by age in Year 7 accounting for the overall effects of the RSV prevention strategies, which include both the direct and indirect effects among the vaccinated age groups and the indirect effects among the unvaccinated age groups. The color shadows show the 95% prediction intervals for the different scenarios as indicated by the legend.