TABLE 2.
Baseline Characteristics of Patients Who Underwent PFO Closure and Patients Who Received Medical Therapy
| PFO Closure (n = 383) | Medical Therapy (n = 208) | p Value | |
|---|---|---|---|
| Age, yrs | 48.6 ± 12.1 | 53.2 ± 15.4 | <0.001 |
|
| |||
| Female | 171 (44.6) | 111 (53.4) | 0.043 |
|
| |||
| BMI, kg/m2 | 27.0 ± 7.7 | 27.0 ± 9.2 | 0.974 |
|
| |||
| Medical history | |||
| Hypertension | 117 (30.5) | 93 (44.7) | 0.001 |
| Diabetes mellitus | 23 (6.0) | 29 (13.9) | 0.001 |
| Hypercholesterolemia | 134 (35.0) | 90 (43.3) | 0.047 |
| CAD history | 12 (3.1) | 20 (9.6) | 0.001 |
| Smoking status | |||
| Current | 56 (14.6) | 30 (14.4) | 0.948 |
| Former | 22 (5.7) | 26 (12.5) | 0.004 |
| Family history of stroke | 83 (21.7) | 36 (17.3) | 0.206 |
|
| |||
| Interatrial septal mobility | |||
| Atrial septal aneurysm | 82 (21.4) | 23 (11.1) | 0.002 |
| Hypermobility | 70 (18.3) | 30 (14.4) | 0.233 |
|
| |||
| Interatrial right-to-left shunt size | |||
| Small | 104 (27.2) | 105 (50.5) | <0.001 |
| Medium | 98 (25.6) | 38 (18.3) | 0.044 |
| Large | 181 (47.3) | 65 (31.3) | <0.001 |
|
| |||
| Thrombophilia | 89 (23.2) | 45 (21.6) | 0.657 |
Values are mean ± SD or n (%).
PFO = patent foramen ovale; other abbreviations as in Table 1.