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. 2022 Oct 13;13:1019972. doi: 10.3389/fimmu.2022.1019972

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Copyright © 2022 Ma and Bu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathological characteristics of muscle biopsy in SRP-IMNM. (A), dystrophin combined with eosin staining reveals necrosis myofibers (asterisk). (B), immunohistochemical staining of Neural Cell Adhesion Molecule1 (NCAM1)/CD56 shows scattered myofiber regeneration. Inflammatory cell analysis demonstrates scattered or focal CD68⁺ macrophage infiltration and myophagocytosis (C), scattered CD4⁺ (D) and CD8⁺ T lymphocyte (E), and a few CD20⁺B lymphocytes (F). Magnification (A-F): 200x. These pictures are cited from our previous study (7, 63).