Table 2.

HIS Characteristics of variants. HISPANIC.

CHROM	LOCUS	POS	ID	REF	ALT	A1	A1_CT	ALLELE_CT	A1_CASE_CT	A1_CTRL_CT	CASE_ALLELE_CT	CTRL_ALLELE_CT	CASE_NON_A1_CT	CASE_HET_A1_CT	CASE_HOM_A1_CT	CTRL_NON_A1_CT	CTRL_HET_A1_CT	CTRL_HOM_A1_CT	A1_FREQ	A1_CASE_FREQ	A1_CTRL_FREQ	OBS_CT
1	MTHFR	11794419	rs1801131	T	G	G	137	930	25	112	166	764	59	23	1	279	94	9	0.147	0.151	0.147	465
1	MTHFR	11796321	rs1801133	G	A	A	373	936	65	308	166	770	30	41	12	139	184	62	0.399	0.392	0.400	468
1	PROX1	213985913	rs340874	T	C	C	330	936	50	280	166	770	44	28	11	155	180	50	0.353	0.301	0.364	468
1	LYPLAL1-AS1	219527177	rs2785980	T	C	T	406	936	78	328	166	770	29	30	24	145	152	88	0.434	0.470	0.426	468
1	MTR	236885200	rs1805087	A	G	G	195	938	33	162	166	772	54	25	4	240	130	16	0.208	0.199	0.210	469
2	DPYSL5	26930006	rs1371614	C	T	T	396	934	80	316	164	770	21	42	19	145	164	76	0.424	0.488	0.410	467
2	GCKR	27518370	rs780094	T	C	T	308	930	48	260	164	766	44	28	10	164	178	41	0.331	0.293	0.339	465
2	MAP3K19	134998059	rs1530559	A	G	A	308	934	49	259	164	770	41	33	8	174	163	48	0.330	0.299	0.336	467
2	RBMS1	160460949	rs6742799	A	C	C	130	928	22	108	166	762	62	20	1	279	96	6	0.140	0.133	0.142	464
2	FIGN	163641436	rs2119289	C	G	C	99	938	22	77	166	772	61	22	0	311	73	2	0.106	0.133	0.100	469
2	COBLL1	164694691	rs7607980	T	C	C	65	938	12	53	166	772	71	12	0	335	49	2	0.069	0.072	0.069	469
2	G6PC2	168906638	rs560887	T	C	T	94	938	12	82	166	772	72	10	1	307	76	3	0.100	0.072	0.106	469
2	G6PC2	168917561	rs563694	C	A	C	119	938	15	104	166	772	70	11	2	286	96	4	0.127	0.090	0.135	469
2	IRS1	226203364	rs2943634	A	C	A	190	932	25	165	164	768	61	17	4	247	109	28	0.204	0.152	0.215	466
2	IRS1	226795828	rs1801278	C	T	T	60	938	8	52	166	772	75	8	0	338	44	4	0.064	0.048	0.067	469
3	PPARG	12348985	rs17036328	T	C	C	146	938	21	125	166	772	64	17	2	273	101	12	0.156	0.127	0.162	469
3	PPARG	12351626	rs1801282	C	G	G	123	938	17	106	166	772	67	15	1	291	84	11	0.131	0.102	0.137	469
3	UBE2E2	23413299	rs1496653	A	G	G	107	938	13	94	166	772	71	11	1	299	80	7	0.114	0.078	0.122	469
3	AMT	49417897	rs11715915	C	T	T	140	938	30	110	166	772	58	20	5	289	84	13	0.149	0.181	0.142	469
3	ADCY5	123346931	rs11708067	A	G	G	335	936	54	281	166	770	39	34	10	154	181	50	0.358	0.325	0.365	468
3	SLC2A2	170999732	rs11920090	T	A	A	129	938	19	110	166	772	64	19	0	288	86	12	0.138	0.114	0.142	469
3	IGF2BP2	185793899	rs4402960	G	T	T	237	938	51	186	166	772	41	33	9	222	142	22	0.253	0.307	0.241	469
3	IGF2BP2	185795604	rs7651090	A	G	G	232	934	50	182	166	768	41	34	8	221	144	19	0.248	0.301	0.237	467
3	ADIPOQ	186853103	rs2241766	T	G	G	168	938	32	136	166	772	54	26	3	259	118	9	0.179	0.193	0.176	469
4	WFS1	6288259	rs4458523	T	G	T	292	926	46	246	162	764	38	40	3	174	170	38	0.315	0.284	0.322	463
4	FAM13A	88820118	rs3822072	G	A	A	401	934	72	329	166	768	26	42	15	121	197	66	0.429	0.434	0.428	467
4	TET2	105160479	rs9884482	T	C	C	398	934	62	336	166	768	33	38	12	123	186	75	0.426	0.373	0.438	467
4	PDGFC	156798972	rs4691380	C	T	T	325	932	64	261	166	766	34	34	15	171	163	49	0.349	0.386	0.341	466
5	IRX1	4355595	rs17727202	T	C	C	40	938	5	35	166	772	78	5	0	351	35	0	0.043	0.030	0.045	469
5	ANKRD55	56510924	rs459193	A	G	A	219	934	47	172	166	768	46	27	10	235	126	23	0.234	0.283	0.224	467
5	ZBED3	77130042	rs7708285	G	A	G	338	938	62	276	166	772	30	44	9	164	168	54	0.360	0.373	0.358	469
5	PCSK1	96207022	rs13179048	C	A	A	173	936	25	148	166	770	59	23	1	253	116	16	0.185	0.151	0.192	468
5	PCSK1	96295001	rs17085593	C	G	G	182	938	27	155	166	772	57	25	1	248	121	17	0.194	0.163	0.201	469
5	PCSK1	96393194	rs6235	C	G	G	182	938	27	155	166	772	56	27	0	251	115	20	0.194	0.163	0.201	469
6	RRB1	7212967	rs17762454	C	T	T	360	936	70	290	166	770	29	38	16	148	184	53	0.385	0.422	0.377	468
6	RREB1	7231610	rs9379084	G	A	A	51	938	7	44	166	772	76	7	0	344	40	2	0.054	0.042	0.057	469
6	CDKAL1	20679478	rs7756992	A	G	G	288	934	57	231	166	768	36	37	10	190	157	37	0.308	0.343	0.301	467
6	CDKAL1	20686765	rs9368222	C	A	A	212	938	48	164	166	772	40	38	5	241	126	19	0.226	0.289	0.212	469
6	RSPO3	127131790	rs2745353	C	T	C	376	938	60	316	166	772	35	36	12	125	206	55	0.401	0.361	0.409	469
7	DGKB	15024684	rs2191349	G	T	T	384	936	78	306	166	770	20	48	15	132	200	53	0.410	0.470	0.397	468
7	GCK	44189469	rs1799884	C	T	T	180	936	38	142	166	770	51	26	6	258	112	15	0.192	0.229	0.184	468
7	GCK	44196069	rs4607517	G	A	A	168	928	32	136	162	766	54	22	5	261	108	14	0.181	0.198	0.178	464
7	GRB10	50690548	rs933360	C	T	C	341	936	72	269	166	770	29	36	18	166	169	50	0.364	0.434	0.349	468
7	GRB10	50723882	rs6943153	T	C	C	460	932	76	384	166	766	24	42	17	94	194	95	0.494	0.458	0.501	466
7	HIP1	75546898	rs1167800	A	G	G	285	938	50	235	166	772	42	32	9	186	165	35	0.304	0.301	0.304	469
8	PPP1R3B	9326086	rs4841132	A	G	A	226	936	39	187	164	772	49	27	6	219	147	20	0.241	0.238	0.242	468
8	PPP1R3B	9330085	rs7004769	A	G	A	367	938	63	304	166	772	30	43	10	135	198	53	0.391	0.380	0.394	469
8	ANK1	41651740	rs12549902	G	A	G	387	932	72	315	164	768	27	38	17	124	205	55	0.415	0.439	0.410	466
8	SLC30A8	117172544	rs13266634	C	T	T	235	936	43	192	166	770	48	27	8	219	140	26	0.251	0.259	0.249	468
8	SLC30A8	117172786	rs3802177	G	A	A	232	938	41	191	166	772	49	27	7	222	137	27	0.247	0.247	0.247	469
8	SLC30A8	117173494	rs11558471	A	G	G	244	938	44	200	166	772	47	28	8	216	140	30	0.260	0.265	0.259	469
9	GLIS3	4287466	rs7041847	A	G	G	394	936	57	337	166	770	37	35	11	121	191	73	0.421	0.343	0.438	468
9	GLIS3	4289050	rs7034200	C	A	C	461	936	71	390	166	770	27	41	15	93	194	98	0.493	0.428	0.506	468
9	GLIS3	4293150	rs10814916	A	C	A	433	932	66	367	166	766	28	44	11	105	189	89	0.465	0.398	0.479	466
9	CDKN2B	22134095	rs10811661	T	C	C	119	934	24	95	166	768	60	22	1	295	83	6	0.127	0.145	0.124	467
9	SARDH	133734024	rs573904	C	T	T	201	934	36	165	166	768	51	28	4	234	135	15	0.215	0.217	0.215	467
10	CDC123	12265895	rs11257655	C	T	T	245	938	46	199	166	772	44	32	7	213	147	26	0.261	0.277	0.258	469
10	CDC123	12286011	rs12779790	A	G	G	135	936	23	112	166	770	61	21	1	282	94	9	0.144	0.139	0.145	468
10	CUBN	17114152	rs1801222	A	G	A	245	936	39	206	166	770	51	25	7	200	164	21	0.262	0.235	0.268	468
10	HKDC1	69223185	rs4746822	C	T	T	457	936	84	373	166	770	22	38	23	105	187	93	0.488	0.506	0.484	468
10	HHEX	92722319	rs7923866	C	T	C	466	936	90	376	166	770	17	42	24	104	186	95	0.498	0.542	0.488	468
10	ADRA2A	111282335	rs10885122	T	G	T	172	938	37	135	166	772	54	21	8	262	113	11	0.183	0.223	0.175	469
10	TCF7L2	112994312	rs34872471	T	C	C	192	938	29	163	166	772	58	21	4	240	129	17	0.205	0.175	0.211	469
10	TCF7L2	112996282	rs4506565	A	T	T	215	936	38	177	166	770	52	24	7	228	137	20	0.230	0.229	0.230	468
10	TCF7L2	112998590	rs7903146	C	T	T	190	936	30	160	166	770	57	22	4	240	130	15	0.203	0.181	0.208	468
11	DUSP8	1675619	rs2334499	C	T	T	425	934	85	340	166	768	23	35	25	123	182	79	0.455	0.512	0.443	467
11	KCNJ11	17387083	rs5215	C	T	C	294	932	55	239	166	766	36	39	8	185	157	41	0.315	0.331	0.312	466
11	CRY2	45851540	rs11605924	A	C	C	468	938	72	396	166	772	23	48	12	95	186	105	0.499	0.434	0.513	469
11	MADD	47314769	rs7944584	A	T	T	138	938	24	114	166	772	60	22	1	283	92	11	0.147	0.145	0.148	469
11	OR4S1	48311808	rs1483121	G	A	A	57	938	14	43	166	772	70	12	1	344	41	1	0.061	0.084	0.056	469
11	FADS1	61804006	rs174550	T	C	T	359	928	62	297	164	764	37	28	17	160	147	75	0.387	0.378	0.389	464
11	ARAP1	72721940	rs11603334	G	A	A	71	936	8	63	166	770	76	6	1	326	55	4	0.076	0.048	0.082	468
11	MTNR1B	92940662	rs1387153	C	T	T	163	936	38	125	166	770	50	28	5	270	105	10	0.174	0.229	0.162	468
11	MTNR1B	92965261	rs10830962	C	G	G	309	938	62	247	166	772	34	36	13	182	161	43	0.329	0.373	0.320	469
11	MTNR1B	92975544	rs10830963	C	G	G	124	938	27	97	166	772	56	27	0	294	87	5	0.132	0.163	0.126	469
12	GLS2	56471554	rs2657879	A	G	G	234	938	34	200	166	772	53	26	4	212	148	26	0.249	0.205	0.259	469
12	IGF1	102481791	rs35767	A	G	A	239	936	50	189	166	770	39	38	6	219	143	23	0.255	0.301	0.245	468
12	HNF1A	121022883	rs7957197	T	A	A	106	938	18	88	166	772	66	16	1	310	64	12	0.113	0.108	0.114	469
12	P2RX2	132465032	rs10747083	G	A	G	243	938	37	206	166	772	52	25	6	201	164	21	0.259	0.223	0.267	469
13	PDX1	27917061	rs2293941	G	A	A	277	938	53	224	166	772	35	43	5	206	136	44	0.295	0.319	0.290	469
13	KL	32980164	rs576674	G	A	G	344	934	60	284	164	770	31	42	9	161	164	60	0.368	0.366	0.369	467
14	WARS	100372924	rs3783347	G	T	T	96	938	14	82	166	772	69	14	0	308	74	4	0.102	0.084	0.106	469
15	C2CD4A	62090956	rs4502156	T	C	T	289	936	50	239	166	770	43	30	10	184	163	38	0.309	0.301	0.310	468
15	C2CD4B	62141763	rs11071657	A	G	A	393	936	65	328	166	770	34	33	16	138	166	81	0.420	0.392	0.426	468
16	FTO	53767042	rs1421085	T	C	C	151	938	22	129	166	772	61	22	0	267	109	10	0.161	0.133	0.167	469
16	FTO	53782363	rs8050136	C	A	A	195	938	31	164	166	772	54	27	2	240	128	18	0.208	0.187	0.212	469
16	CTRB2	75211105	rs9921586	G	T	T	118	938	19	99	166	772	65	17	1	298	77	11	0.126	0.114	0.128	469
17	GLP2R	9888058	rs17676067	T	C	C	109	936	23	86	166	770	62	19	2	301	82	2	0.116	0.139	0.112	468
17	HNF1B	37738049	rs4430796	A	G	G	322	938	66	256	166	772	32	36	15	181	154	51	0.343	0.398	0.332	469
19	CILP2	19547663	rs16996148	G	T	T	57	938	13	44	166	772	71	11	1	343	42	1	0.061	0.078	0.057	469
19	PEPD	33408159	rs731839	G	A	G	416	934	78	338	164	770	22	42	18	118	196	71	0.445	0.476	0.439	467
19	GIPR	45693376	rs2302593	C	G	C	387	934	83	304	166	768	21	41	21	146	172	66	0.414	0.500	0.396	467
20	FOXA2	22578963	rs6048205	A	G	G	50	938	12	38	166	772	72	10	1	352	30	4	0.053	0.072	0.049	469
20	TOP1	41115265	rs6072275	G	A	A	118	938	20	98	166	772	65	16	2	293	88	5	0.126	0.120	0.127	469
20	ZHX3	41203988	rs17265513	T	C	C	72	938	15	57	166	772	69	13	1	330	55	1	0.077	0.090	0.074	469
20	SLC17A9	62967547	rs3746750	A	G	A	314	934	63	251	164	770	30	41	11	167	185	33	0.336	0.384	0.326	467
21	BACE2	41209710	rs737288	G	T	T	194	934	39	155	164	770	52	21	9	246	123	16	0.208	0.238	0.201	467
21	BACE2	41211811	rs6517656	G	A	A	167	936	36	131	166	770	55	20	8	270	99	16	0.178	0.217	0.170	468

Main characteristics of the variants for the Hispanic (HIS) ethnicity.

CHROM, Chromosome code; LOCUS, Locus/Gene; POS, Base-pair coordinate [GRCh38]; ID, Variant ID; REF, Reference allele; ALT, Alternate allele; A1, Counted allele in logistic regression; A1_CT, Total A1 allele count; ALLELE_CT, Allele observation count; A1_CASE_CT, A1 count in cases; A1_CTRL_CT, A1 count in controls; CASE_ALLELE_CT, Case allele observation count; CTRL_ALLELE_CT, Control allele observation count; CASE_NON_A1_CT, Case genotypes with 0 copies of A1; CASE_HET_A1_CT, Case genotypes with 1 copy of A1; CASE_HOM_A1_CT, Case genotypes with 2 copies of A1; CTRL_NON_A1_CT, Control genotypes with 0 copies of A1; CTRL_HET_A1_CT, Control genotypes with 1 copy of A1; CTRL_HOM_A1_CT, Control genotypes with 2 copies of A1; A1_FREQ, A1 allele frequency; A1_CASE_FREQ, A1 allele frequency in cases; A1_CTRL_FREQ, A1 allele frequency in controls; OBS_CT, Number of samples in the regression.